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What prokinetic drug can be used to help treat Obstipation megacolon in the cat?

What prokinetic drug can be used to help treat Obstipation megacolon in the cat?

Cisapride is often the prokinetic of choice. It has been shown to improve smooth muscle cell contraction in vitro, but the in vivo benefits of this medication for feline idiopathic megacolon are unproven. Nonetheless, it remains a rational and anecdotally supported medication to use.

Can megacolon in cats be cured without surgery?

Cats with pelvic obstruction secondary to pelvic trauma can be treated by removal of the abnormal pelvic bones (pelvic ostectomy) to allow normal passage of feces again. Unfortunately, if the megacolon has been present for greater than four to six months, dilation and loss of function may be irreversible.

Is it safe to give my cat Zantac?

Do not give Zantac to cats who are sensitive or allergic to the drug. Use with care, and possibly at a reduced dose in cats with diminished kidney or liver function. Your veterinarian may recommend close monitoring of liver enzymes. Do not give Zantac to lactating cats.

What does it mean when a cat has a megacolon?

Megacolon in cats literally means enlarged colon. It happens when the large intestine is filled with fecal matter which causes it to enlarge beyond its normal diameter. Here is more: When does Megacolon Occur? Which are Cats Most Susceptible to Megacolon? Cats tend not to chew their food but rather swallow in chunks.

How much cisapride to take for megacolon in cats?

The starting dose is 2.5 mg BID, but can be titrated upwards as needed to 5-7.5 mg TID. Cisapride is no longer available for human use due to its arrhythmogenicity, but it can be gotten from compounding pharmacies for veterinary use.

What should I Feed my Cat with megacolon?

Meat diets for severe megacolon disorder as cats are “obligated carnivores “intensely drawn to moist foods that are highly packed with amino acids Adoption of a highly digestible, low deposit diet where almost all is used up in the cat’s body and fewer remnants excreted.