Can glargine be given twice daily?
Because of its long duration of action insulin glargine is usually prescribed once daily. However, several reports have shown that the administration of insulin glargine once daily is not enough to achieve adequate glucose control in some patients requiring a twice daily dosing [2], [3], [4], [5], [6], [7], [8], [9].
How many units of Lantus should a Type 2 diabetic?
Dosage for type 2 diabetes The usual starting dose of Lantus for people with type 2 diabetes is 0.2 units/kg. (There are about 2.2 lb/kg.) The maximum starting dose of Lantus is 10 units a day. Lantus is typically taken once a day, not twice a day.
How long is Glargine good for cats?
Insulin glargine has a shelf-life of 4 weeks once opened and kept at room temperature. We have found that opened vials stored in the refrigerator can be used for up to 6 months.
How much glargine can a diabetic cat take?
In some cases, there is a “grey zone” of peak 11 – 14 mmol/L and nadir 3 – 4 mmol/l glucose concentrations. In these cases, the glargine insulin dose may be maintained or decreased depending on the water intake, urine glucose, clinical signs and length of time the cat has been treated with insulin.
How often to give glargine’s / C to ketoacidotic cats?
Ketoacidotic cats may be treated with glargine s/c at the above dose rates in combination with regular insulin IM or IV (we have found IU regular insulin IM every 2-4 hours based on glucose conc works best). This regime is continued until hydration restored and appetite reteurns, which usually occurs in 1-3 days. 1.
When to withhold insulin in cats with diabetes?
After a minimum of 2 weeks of insulin therapy, if the pre-insulin blood glucose is < <180mg/dL (<10mmol/L) and insulin dose is ½-1 U SID, insulin should be withheld and a 12hr glucose curve performed.
When to use glargine bid or SID for diabetic cats?
Poorly controlled or unstable diabetic cats (glargine’s long duration of action is likely to benefit these cats) When SID dosing is desired or demanded (It is important to note that better glycaemic control and higher remission rates will be obtained with BID dosing. SID dosing only provides similar control and remission rates to lente BID)
How often can you give a diabetic cat glargine?
Use 0.5-1U BID or once daily until insulin is withdrawn. Some cats that have been treated with other insulin will go into remission, usually within 1-4 months after instituting glargine. Remission in cats that have been treated for more than 2 years is extremely rare.
Ketoacidotic cats may be treated with glargine s/c at the above dose rates in combination with regular insulin IM or IV (we have found IU regular insulin IM every 2-4 hours based on glucose conc works best). This regime is continued until hydration restored and appetite reteurns, which usually occurs in 1-3 days. 1.
When does glargine in cats go into remission?
Some cats that have been treated with other insulin will go into remission, usually within 1-4 months after instituting Glargine. Remission in cats that have been treated for more than 2 years is extremely rare. Remission is likely to occur if the nadir glucose is in the normal range and pre-insulin blood glucose is less than 216 mg/dL (12 mmol/l).
Poorly controlled or unstable diabetic cats (glargine’s long duration of action is likely to benefit these cats) When SID dosing is desired or demanded (It is important to note that better glycaemic control and higher remission rates will be obtained with BID dosing. SID dosing only provides similar control and remission rates to lente BID)